We are also developing new methods for tracking individual proteins molecules in living cells at ms time resolution (English et al. PNAS 2011).
The generalization of zero order kinetics to several dimensions (Elf et al. Biophys J, 2003, Genome Res, 2003), that implies that the substrate pools to multi substrate reactions can display huge stochastic fluctuations and ultra sensitivity because the increase in one pool is compensated by the decrease in an other so that the overall flux is conserved. The observation has consequences for the flux of amino acids in protein synthesis (Biophys J, 2005).
New theoretical methods to analyze stochastic processes makes it possible to investigate the consequences of time delays in gene regulatory control circuits (Grönlund et al. PNAS 2009, Nature Communications 2010)